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Product

LEND: Infrared Thermal Analysis and Individual Differences in Skin Temperature Asymmetry in Rett Syndrome

Center:

MN-Institute on Community Integration, UCEDD/LEND

Fiscal Year:

2015

Contact Information:

Frank Symons
[email protected]
612-626-8697

Product Description:

We evaluated the feasibility of using a portable infrared thermal camera to quantify the degree of thermal dysregulation (cold hands/feet) and test for naturally occurring within-patient skin temperature asymmetry in Rett syndrome. There were large intraindividual left/right differences in temperature. Seven (47%) and eight (53%) patients had statistically significant (P <0.05) left/right asymmetries between hands (mean difference = 0.87C, standard deviation = 1.21) and feet (mean difference = 1.73C, standard deviation = 3.03), respectively. The degree of thermal asymmetry may reflect prolonged activity of the sympathetic nervous system and individual differences in sympathetic regulation. As clinical trials emerge and endpoints are considered, portable infrared thermal camera may provide one noninvasive means of evaluating changes in sympathetic regulation.

Keyword(s):

Product/Publication Type(s):

Peer-reviewed publications in scholarly journals Published/In Press

Target Audience:

Professionals

Alternative Format:

To Obtain Copies (URL or Email):

http://www.sciencedirect.com/science/article/pii/S0887899415001587#

COVID-19 Related Data:

N/A

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