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Autonomic Nerve Function and Ghrelin Levels in Adults with Cyclic Vomiting Syndrome.

Center:
Fiscal Year:
2010
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Product Description:
DYSAUTONOMIA IN PATIENTS WITH CYCLIC VOMITING SYNDROME (CVS) Protocol Objective: The objective of this study is to determine if dysautonomia and ghrelin levels predispose towards Cyclic Vomiting (CVS), therefore demonstrating that autonomic functioning and the ghrelin hormone are important factors in the pathogenesis of CVS as a whole. Specific Aims: The main purpose of research is to benefit future patients and society in general. To discover how common autonomic dysfunction is in individuals with cyclic vomiting syndrome therefore contributing to treatment considerations. This study may help the investigators learn more about cyclic vomiting syndrome. Consequently, this may lead to the development of future diagnostic tests or therapies. Research Design: This is a prospective design to determine the presence of dysautonomia and ghrelin levels in a population of adult patients with CVS. Methods to Achieve Goals: This research study will be conducted at The Center for Gastrointestinal Nerve & Muscle Function, Department of Internal Medicine at Kansas University Medical Center (KUMC), Kansas City, KS. with Richard W. McCallum, M.D., as the principal investigator. Autonomic studies will be performed by Rebecca Flann at the Landon Center for the Aging, just north of the main campus. Approximately 35 subjects will be enrolled at KUMC.
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Product/Publication Type(s):
Conference presentations and posters presented
Target Audience:
Consumers/Families, Professionals, Students
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