|

AUCD Community Inclusion

AUCD’s Community Inclusion Team supports the University Centers for Excellence in Developmental Disabilities (UCEDD) Network in partnership with the Administration for Community Living.

Learn More
|

AUCD Maternal and Child Health Engagement

AUCD’s Maternal and Child Health Engagement supports the Autism CARES Programs, including LEND and DBP Programs.

Learn More
|

AUCD Public Health

AUCD’s Public Health Team works to create health promotion and public health efforts that include people with disabilities.

Learn More
|

AUCD Emerging Leaders Community

AUCD Emerging Leaders are a part of a community that includes trainees, early career professionals, self-advocates, and family members from AUCD member Centers and Programs.

Learn More

Donate

Product

Lymphoma Cytogenetics

Center:

NE-Munroe-Meyer Institute of Genetics & Rehabilitation, UCEDD/LEND

Fiscal Year:

2012

Contact Information:

Warren Sanger
[email protected]
402-559-6328

Product Description:

The historical significance of lymphoma cytogenetics is accentuated by the fact that a distinct chromosomal abnormality, ?14q+?, was first identified and associated with Burkitt lymphoma.1 This triggered numerous investigations in search of specific chromosomal abnormalities in various malignancies,. However, the maximum success came from chromosome studies in hematologic malignancies because they readily lent themselves to cytogenetic analysis. The characterization of t(8;14)(q24;q32) and its association with Burkitt lymphoma2 led to focused genetic studies in various subtypes of lymphomas. Since then, cytogenetics has played a crucial role in providing substantial insight into the genetic mechanisms of lymphomagenesis. Consistent chromosomal alterations in lymphomas, specifically, non-Hodgkin lymphomas (NHLs), have greatly impacted the classification of NHLs in general, especially the B-cell lymphomas,3-5.

Keyword(s):

Lymphoma, Cytogenetics, Fluorescence in situ hybridization, Microarray, Disease progression

Product/Publication Type(s):

Peer-reviewed publications in scholarly journals Published/In Press

Target Audience:

Professionals, Students

Alternative Format:

To Obtain Copies (URL or Email):

[email protected]

COVID-19 Related Data:

N/A

1100 Wayne Avenue, Suite 1000 Silver Spring, MD 20910