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Product

Microarray Facilitates Cytogenetic Definition of Secondary Abnormalities in ALCL

Center:

NE-Munroe-Meyer Institute of Genetics & Rehabilitation, UCEDD/LEND

Fiscal Year:

2013

Contact Information:

Warren Sanger
[email protected]
402-559-6328

Product Description:

Anaplastic large cell lymphoma (ALCL) accounts for 8-10% of pediatric non Hodgkin lymphomas and is most often characterized by a recurrent rearrangement of the ALK (anaplastic lymphoma kinase) gene at chromosome region 2p23. The t(2;5)(p23;q35) is noted in 83% of pediatric cases; however, secondary genetic abnormalities generally dictate the disease progression and hence a comprehensive study of these alterations at diagnosis is helpful. A combined use of cytogenetics and microarray provides more comprehensive information of secondary abnormalities giving a better understanding of the underlying genetics of disease progression.

Keyword(s):

Product/Publication Type(s):

Conference presentations and posters presented

Target Audience:

Professionals, Students

Alternative Format:

To Obtain Copies (URL or Email):

[email protected]

COVID-19 Related Data:

N/A

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