Children's National Hospital

URL: https://research.childrensnational.org/labs/dc-iddrc/core-services/cell-and-tissue

Description

The Cell and Tissue Microscopy Core (CTMC) supports the District of Columbia Intellectual and Developmental Disability Research Center (DC-IDDRC) researchers in their work that is reliant on the use of high-resolution optical and electron microscopic approaches to study cells and tissues

URL: https://research.childrensnational.org/labs/dc-iddrc/core-services/clinical-translational

Description

The overall goal of the Clinical Translational Core (CTC) is to efficiently and effectively move basic and applied intellectual and developmental disability research (IDDR) findings into human clinical trials and ultimately clinical practice. The CTC provides assistance and services to IDDRC investigators at each stage of the clinical and translational research. This process is facilitated by a support team and navigators.

URL: https://research.childrensnational.org/labs/dc-iddrc/core-services/genomics-and-bioinformatics

Description

The Genomics and Bioinformatics Core (GBC) delivers cost-effective analytical genomics solutions and bioinformatics analyses for intellectual and developmental disabilities (IDD) researchers. The objective of the GBC is to maximize the potential for researchers to develop new insights, diagnostics and therapeutic interventions for individuals with IDD by removing obstacles for leveraging genomic methods.

URL: https://research.childrensnational.org/labs/dc-iddrc/core-services/human-and-animal-imaging

Description

The Human and Animal Imaging Core (HAIC) provides non-invasive in vivo investigation of disease mechanisms in human and in animal models, effects of IDDs and their causes on brain structure and function, expression and perturbation of cognitive networks in IDDs, and identification of IDD/brain injury biomarkers. The HAIC provides access to state-of-the-art in vivo whole brain imaging technologies and expertise to DC-IDDRC investigators in order to support, facilitate and enhance IDD-targeted research in humans and in animal models. To achieve the Core’s aims we have established advanced imaging facilities at three collaborating DC-IDDRC institutions — Howard University (HU), Georgetown University (GU) and Children’s National Hospital (CNH) — which provide integrated structural and functional imaging of animal models and human populations.

URL: https://research.childrensnational.org/labs/dc-iddrc/core-services/neurobehavioral

Description

The mission of the Neurobehavioral Evaluation Core (NEC) is to provide the District of Columbia Intellectual and Developmental Disabilities Research Center (DC-IDDRC) investigators with resources to link underlying biological mechanisms of neurodevelopmental disorders with behavioral and cognitive outcomes as measured in humans and animal models.