UNC Intellectual and Developmental Disabilities Research Center

University of North Carolina
101 Renee Lynne Ct, Carrboro, NC 27510
Campus Box 7255
Chapel Hill, NC, 27599-7255
919-843-8641

The Carolina Institute for Developmental Disabilities - Intellectual and Developmental Disabilities Research Center (IDDRC) maintains five research core facilities, throughout the UNC campus, to support funded investigators conducting research relevant to understanding the pathogenesis and treatment of intellectual and developmental disabilities. The IDDRC at the Carolina Institute for Developmental Disabilities provides core research and administrative support to bring together a diverse group of investigators throughout UNC and the Institute. Center investigators come from over 20 Departments throughout the campus including Cell and Molecular Physiology, Cell and Developmental Biology, Biochemistry and Biophysics, Microbiology and Immunology, Neurology, Psychiatry, Pediatrics, Pathology and Laboratory Medicine, Pharmacology, Psychology, Nutrition, Epidemiology, Computer Science, Allied Health Sciences, Social Medicine, Biomedical Engineering, and Genetics. The IDDRC provides a focal point for bringing together investigators from five major University colleges and schools including Medicine, Arts and Sciences, Education, Nursing and Public Health. Major research themes in the IDDRC include:

Gene-brain-behavior relationships in neurogenetic syndromes
Basic Neuroscience
Behavioral development in normal and at risk populations
Interventions - including Psychopharmacology, Early Educ/Behavioral Intervention & Studies of Service Delivery & Cultural Factors in IDD.

Program Website

CORE(s)

Core values are the internal compass of fundamental principles that drive the work of IDDRCs.

URL: http://www.cidd.unc.edu/Research/default.aspx?id=25

Description

The Behavioral Measurement Core supports efforts to integrate human and animal studies of neurodevelopmental disorders through a focus on specific behavioral markers and specific behavioral processes in both humans and mouse models of human disease.

The core is composed of two laboratories: the Human Behavioral Phenotyping Laboratory and the Mouse Behavioral Phenotyping Laboratory . These facilities are available for all aspects of state-of-the-art measurement of mouse behavior and selected aspects of human behavior; training in behavioral measurement and consultation regarding the interface of rodent models of human behavioral condidtions with human studies.

Services

Human Behavioral Phenotyping Laboratory

Use of Observational Laboratory
Use of eye-movement monitoring
Use of Miniloggers to record heart rate or activity
Consultation on measurement
Consultation on recording data
Consultation on observational coding
Use of audio-visual equipment

Mouse Behavioral Phenotyping Laboratory

URL: http://www.cidd.unc.edu/Research/default.aspx?id=23

Keywords Data management; statistical analysis; statistical and data management assistance

Description

The overall objectives of the Data Management and Statistical Analysis Core (DMSA) are to enhance the productivity of NDRC investigators and to enhance the quality of their research. The DMSA continues to meet its goals to assist MRDDRC projects with study design, data management, and statistical analysis. This assistance has ranged from simple consultation to answering specific data management or analysis questions, to collaborative involvement from the design stage through proposal writing, data collection and management, to the publication of results.

Services

The Data Management and Statistical Analysis Core provides services through every stage of a research project including:

writing grant proposals;
developing efficient experimental designs;
designing data collection instruments and conducting pilot tests;
designing and implementing database management systems;
supervising execution of the study and collection of data;
operating database management systems to clean, store, and retrieve and archive data;
performing statistical analyses and writing research papers and reports

URL: http://www.cidd.unc.edu/Registry/

Keywords Subject registry; autism; Fragile X; study participants; research subjects

Description

The Research Participant Registry Core maintains databases of individuals and families who are interested in participating in research to help IDDRC investigators recruit qualified research participants. The Research Participant Registry Core provides an organized and confidential way to identify and contact potential participants who are eligible for participation in particular studies.

Services

The Research Participant Registry Core serves investigators by assisting in the recruitment of human participants for research by:

populating and maintaining participant databases for recruitment purposes
assisting investigators with grant preparation and recruitment materials
contacting potential participants on behalf of research projects while maintaining confidentiality
coordinating recruitment among studies to limit the potential for over-contact in selected samples and to encourage collaboration and efficient use of resources
promoting UNC research projects to constituent groups with exhibits, presentations, and products
contacting registry members annually to maintain current demographic information and share research findings

The Registry Database is used to recruit appropriate research participants in an efficient and timely manner and to track them over time.

AUCD Community Inclusion

AUCD Maternal and Child Health Engagement

AUCD Public Health

AUCD Emerging Leaders Community

Who We Are

Initiatives

UNC Intellectual and Developmental Disabilities Research Center

University of North Carolina 101 Renee Lynne Ct, Carrboro, NC 27510 Campus Box 7255 Chapel Hill, NC, 27599-7255 919-843-8641

CORE(s)

Behavioral Measurement Core

Data Management and Statistical Analysis

Research Participant Registry Core

University of North Carolina
101 Renee Lynne Ct, Carrboro, NC 27510
Campus Box 7255
Chapel Hill, NC, 27599-7255
919-843-8641