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Product

Gestational Vitamin 25(OH)D Status as a Risk Factor for Receptive Language Development: A 24-Month, Longitudinal, Observational Study

Center:

TN-Center on Developmental Disabilities, UCEDD/LEND

Fiscal Year:

2016

Contact Information:

Joyce Carolyn Graff
[email protected]
901-448-3066

Product Description:

Emerging data suggest that vitamin D status during childhood and adolescence can affect neurocognitive development. The purpose of this study was to investigate whether gestational 25(OH)D status is associated with early childhood cognitive and receptive language development. The CANDLE Study study enrolled 1503 mother-child dyads during the second trimester of healthy singleton pregnancies from Shelby County TN. Among 1020 participants of the total CANDLE cohort for whom 25(OH)D levels were available, mean gestational 25(OH)D level during the second trimester was 22.3 ng/mL (range 5.968.4), with 41.7% of values <20 ng/dL. Cognitive and language scaled scores increased in a stair-step manner as gestational 25(OH)D levels in the second trimester rose from <20 ng/dL, through 2029.99 ng/dL, to 30 ng/dL. When controlling for socioeconomic status, race, use of tobacco products, gestational age of the child.

Keyword(s):

vitamin D;, language development, cognitive development, prenatal nutrition, gestation

Product/Publication Type(s):

Peer-reviewed publications in scholarly journals Published/In Press

Target Audience:

Consumers/Families, Professionals, Policymakers, Students

Alternative Format:

To Obtain Copies (URL or Email):

doi:10.3390/nu7125499

COVID-19 Related Data:

N/A

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