Copy-number variations associated with neuropsychiatric conditions. Nature, 2008,455:919-923.

2009

Leadrshp Ed in Neurodev Dis LEND
[email protected]
312-996-1792

Cook, Jr., E. H., Scherer, S. W. (2008). Copy-number variations associated with neuropsychiatric conditions. Nature, 455, 919-923. - Neuropsychiatric conditions such as autism and schizophrenia have long been attributed to genetic alterations, but identifying the genes responsible has proved challenging. Microarray experiments have now revealed abundant copy-number variation ? a type of variation in which stretches of DNA are duplicated, deleted and sometimes rearranged ? in the human population. Genes affected by copy-number variation are good candidates for research into disease susceptibility. The complexity of neuropsychiatric genetics, however, dictates that assessment of the biomedical relevance of copy-number variants and the genes that they affect needs to be considered in an integrated context.

Peer-reviewed publications in scholarly journals Published/In Press

N/A