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Elevated C-Reactive Protein Associated with Decreased High-Density Lipoprotein Cholesterol in Men with Spinal Cord Injury

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Fiscal Year:
2009
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Liang H, Mojtahedi MC, Chen D, Braunschweig CL*. Elevated C-Reactive Protein Associated with Decreased High-Density Lipoprotein Cholesterol in Men with Spinal Cord Injury Arch Phys Med Rehab. 89:36-41, 2008. - ABSTRACT: OBJECTIVES: To determine if people with spinal cord injury (SCI) have elevated C-reactive protein (CRP), to examine the association of CRP with high-density lipoprotein cholesterol (HDL-C), and to assess the influence of completeness and level of injury on these parameters. PARTICIPANTS: Men with SCI (n=129) who were free of infection and/or recent anti-inflammatory medication use as well as their 1:1 age- and race-matched able-bodied counterparts from the 1999-2002 National Health and Nutrition Examination Surveys. CONCLUSIONS: The elevated CRP, possibly the major risk factor, together with decreased HDL-C may contribute to greater incidence for cardiovascular disease in the SCI population.
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