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Product

Prenatal Substance Exposure: Neurobiologic Organization at 1 Month.

Center:

TN-Center on Developmental Disabilities, UCEDD/LEND

Fiscal Year:

2014

Contact Information:

Toni M. Whitaker
[email protected]
901-448-6511

Product Description:

To examine the autonomic nervous system and neurobehavioral response to a sustained visual attention challenge in 1-month-old infants with prenatal substance exposure. We measured heart rate, respiratory sinus arrhythmia, and neurobehavior during sustained visual orientation tasks included in the Neonatal Intensive Care Unit Network Neurobehavioral Scale in 1129 1-month-old infants with prenatal substance exposure. Problems with arousal regulation were identified in infants with prenatal substance exposure. Autonomic dysregulation has been implicated as a mechanism by which these difficulties occur. Our results suggest that infants with prenatal exposure to both cocaine and opiates have the greatest autonomic response to the challenge of a sustained visual attention task, possibly putting these infants at risk for problems associated with physiologic and behavioral regulation, a necessary prerequisite for early learning.

Keyword(s):

ECG, Electrocardiography, Neonatal Intensive Care Unit Network Neurobehavioral Scale

Product/Publication Type(s):

Peer-reviewed publications in scholarly journals Published/In Press

Target Audience:

Professionals, Policymakers, Students

Alternative Format:

Electronic (disc, CD, 508 compliant web posting)

To Obtain Copies (URL or Email):

doi: 10.1016/j.jpeds.2013.04.033/ [email protected]

COVID-19 Related Data:

N/A